369-35-7
- Product Name：2-Fluoro-4-nitroaniline
- Molecular Formula：C6H5FN2O2
- Purity：99%
- Molecular Weight：156.116
Product Details;
CasNo： 369-35-7
Molecular Formula： C6H5FN2O2
Appearance： WHITE TO TAN POWDER, CRYSTALS OR CRYSTALLINE POWDER AND/OR CHUNKS
factory and supplier 369-35-7 2-Fluoro-4-nitroaniline in stock
- Molecular Formula:C6H5FN2O2
- Molecular Weight:156.116
- Appearance/Colour:WHITE TO TAN POWDER, CRYSTALS OR CRYSTALLINE POWDER AND/OR CHUNKS
- Vapor Pressure:0.000392mmHg at 25°C
- Melting Point:126-130°C
- Refractive Index:1.603
- Boiling Point:317.2 °C at 760 mmHg
- PKA:-0.45±0.10(Predicted)
- Flash Point:145.6 °C
- PSA：71.84000
- Density:1.448 g/cm3
- LogP:2.42050
2-Fluoro-4-nitroaniline(Cas 369-35-7) Usage
|
Purification Methods |
The aniline forms yellow crystals on recrystallisation from aqueous MeOH or EtOH. The acetyl derivative has m 203-204o (from EtOH). [Wepster & Verkade Recl Trav Chim, Pays Bas 68 86 1949, Beilstein 12 III 1647.] |
InChI:InChI=1/C6H5FN2O2/c7-5-3-4(9(10)11)1-2-6(5)8/h1-3H,8H2
369-35-7 Relevant articles
Synthesis and Evaluation of Novel 7- and 8-Aminophenoxazinones for the Detection of β-Alanine Aminopeptidase Activity and the Reliable Identification of Pseudomonas aeruginosa in Clinical Samples
Bedernjak, Alexandre F.,Zaytsev, Andrey V.,Babolat, Michèle,Cellier, Marie,James, Arthur L.,Orenga, Sylvain,Perry, John D.,Groundwater, Paul W.,Anderson, Rosaleen J.
supporting information, p. 4476 - 4487 (2016/06/13)
A series of novel 8-aminophenoxazin-3-on...
Synthesis of 2,5- and 2,6-dinitrofluorobenzenes and related hydroquinones
Behrman,Chen, Ssuhen
, p. 422 - 425 (2007/10/03)
-
A convenient copper-catalyzed direct animation of nitroarenes with 9-alkylhydroxylamines
Seko, Shinzo,Miyake, Kunihito,Kavvamura, Norio
, p. 1437 - 1444 (2007/10/03)
O-Alkylhydroxylamines, particularly O-me...
Nitroarylamines via the Vicarious Nucleophilic Substitution of Hydrogen: Amination, Alkylamination, and Arylamination of Nitroarenes with Sulfenamides
Makosza, Mieczyslaw,Bialecki, Maciej
, p. 4878 - 4888 (2007/10/03)
A new reaction of sulfenamides with elec...
369-35-7 Process route
-
-
399-31-5
N-(2-fluorophenyl)acetamide
-
-
17809-36-8
2-fluoro-6-nitroaniline
-
-
369-35-7
2-fluoro-4-nitroaniline
| Conditions | Yield |
|---|---|
|
N-(2-fluorophenyl)acetamide;
With
sulfuric acid; nitric acid;
In
acetic acid;
at 10 - 20 ℃;
for 2.5h;
With
sodium hydroxide;
In
ethanol; water;
for 5h;
|
15.3% 67.5% |
|
With
hydrogenchloride; nitric acid;
Multistep reaction;
1.) acetic anhydride-acetic acid, 0-5 deg C;
|
-
-
402-67-5
3-fluoro-1-nitrobenzene
-
-
364-78-3
2-nitro-4-fluoroaniline
-
-
17809-36-8
2-fluoro-6-nitroaniline
-
-
369-35-7
2-fluoro-4-nitroaniline
| Conditions | Yield |
|---|---|
|
With
O-Methylhydroxylamin; potassium tert-butylate; copper(l) chloride;
In
N,N-dimethyl-formamide;
for 1h;
Yield given. Yields of byproduct given. Title compound not separated from byproducts;
Ambient temperature;
|
|
|
With
potassium tert-butylate; N,N,N-trimethylhydrazinium iodide;
In
dimethyl sulfoxide;
Yield given. Yields of byproduct given;
Ambient temperature;
|
|
|
With
O-Methylhydroxylamin; potassium tert-butylate;
copper(l) chloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
Title compound not separated from byproducts;
|
369-35-7 Upstream products
-
369-34-6
3,4-difluoronitrobenzene
-
348-19-6
2'-fluoro-4'-nitroacetanilide
-
399-31-5
N-(2-fluorophenyl)acetamide
-
402-67-5
3-fluoro-1-nitrobenzene
369-35-7 Downstream products
-
350-20-9
2-chloro-6-fluoro-4-nitro-aniline
-
160984-02-1
N-(2-fluoro-4-nitrophenyl)-1-cyclohexene-1,2-dicarboximide
-
869335-24-0
N-(2-fluoro-4-nitrophenyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-pyrrolo[2,3-b]pyridin-4-amine
-
869335-25-1
N-(2-fluoro-4-nitrophenyl)-1H-pyrrolo[2,3-b]pyridin-4-amine
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