352-34-1

  • Product Name:1-Fluoro-4-iodobenzene
  • Molecular Formula:C6H4FI
  • Purity:99%
  • Molecular Weight:222.001
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Product Details;

CasNo: 352-34-1

Molecular Formula: C6H4FI

Appearance: colorless to light yellow liquid

factory and supplier 352-34-1 1-Fluoro-4-iodobenzene in stock

  • Molecular Formula:C6H4FI
  • Molecular Weight:222.001
  • Appearance/Colour:colorless to light yellow liquid 
  • Vapor Pressure:9.94E-16mmHg at 25°C 
  • Melting Point:-20 °C(lit.) 
  • Refractive Index:n20/D 1.583(lit.)  
  • Boiling Point:183.7 °C at 760 mmHg 
  • Flash Point:67.9 °C 
  • PSA:0.00000 
  • Density:1.918 g/cm3 
  • LogP:2.43030 

1-fluoro-4-iodobenzene(Cas 352-34-1) Usage

General Description

4-[18F] Fluoroiodobenzene is a versatile building block in 18F radiochemistry and is used in various transition metal-mediated C-C and C-N cross-coupling reactions. Cross-coupling reaction of 4-fluoroiodobenzene with potassium pentafluorophenyltrifluoroborate in the presence of different palladium catalysts and silver oxide in toluene has been investigated.

InChI:InChI=1/C25H20F3NO4/c26-25(27,28)21-12-6-1-7-15(21)13-22(23(30)31)29-24(32)33-14-20-18-10-4-2-8-16(18)17-9-3-5-11-19(17)20/h1-12,20,22H,13-14H2,(H,29,32)(H,30,31)

352-34-1 Relevant articles

PERFLUOROPOLYMER-SUPPORTED FITS REAGENTS

Umemoto, Teruo

, p. 81 - 82 (1984)

Perfluoropolymer-supported FITS reagents...

Oxidative Addition, Transmetalation, and Reductive Elimination at a 2,2′-Bipyridyl-Ligated Gold Center

Harper, Matthew J.,Arthur, Christopher J.,Crosby, John,Emmett, Edward J.,Falconer, Rosalyn L.,Fensham-Smith, Andrew J.,Gates, Paul J.,Leman, Thomas,McGrady, John E.,Bower, John F.,Russell, Christopher A.

, p. 4440 - 4445 (2018)

Three-coordinate bipyridyl complexes of ...

Selective C-H Iodination of (Hetero)arenes

Tanwar, Lalita,B?rgel, Jonas,Lehmann, Johannes,Ritter, Tobias

supporting information, p. 5024 - 5027 (2021/06/30)

Iodoarenes are versatile intermediates a...

Synthesis of biaryl compounds via Suzuki homocoupling reactions catalyzed by metal organic frameworks encapsulated with palladium nanoparticles

Bao, Yan-Sai,Cui, Xin-Yu,Han, Zheng-Bo,Li, Xin,Tang, Hong,Yang, Ming,Zhang, Yu-Yang,Zhao, Kun,Zhou, Mei-Li

, (2020/12/17)

Heterogeneous homocoupling reactions of ...

Palladium-Catalyzed Decarbonylative Iodination of Aryl Carboxylic Acids Enabled by Ligand-Assisted Halide Exchange

Boehm, Philip,Cacherat, Bastien,Lee, Yong Ho,Martini, Tristano,Morandi, Bill

supporting information, p. 17211 - 17217 (2021/07/02)

We report an efficient and broadly appli...

A convenient synthetic approach to a novel class of aryldifluoromethyl pyrimidine derivatives containing strobilurin motif as insecticidal agents

Cai, Zengfei,Cao, Yangyang,Du, Xiaohua,Hao, Shulin,Zhang, Wenliang

supporting information, (2021/10/07)

A series of aryldifluoromethyl pyrimidin...

352-34-1 Process route

4-iodobenzenediazonium tetrafluoroborate
1514-50-7

4-iodobenzenediazonium tetrafluoroborate

iodobenzene
591-50-4

iodobenzene

1-Chloro-4-iodobenzene
637-87-6

1-Chloro-4-iodobenzene

4-fluoro-1-iodobenzene
352-34-1

4-fluoro-1-iodobenzene

Conditions
Conditions Yield
With 18-crown-6 ether; 1,2-dichloro-ethane; at 50 ℃; Rate constant;
32.5 % Chromat.
36.6 % Chromat.
30.9 % Chromat.
C<sub>13</sub>H<sub>11</sub>FN<sub>4</sub>O<sub>3</sub>

C13H11FN4O3

4-fluoro-1-iodobenzene
352-34-1

4-fluoro-1-iodobenzene

2-methoxy-4-nitrophenylamine
97-52-9

2-methoxy-4-nitrophenylamine

Conditions
Conditions Yield
With boron trifluoride diethyl etherate; sodium iodide; In acetonitrile; at 40 ℃; for 3h;

352-34-1 Upstream products

  • 462-06-6
    462-06-6

    fluorobenzene

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    67-56-1

    methanol

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    para-diiodobenzene

  • 1514-50-7
    1514-50-7

    4-iodobenzenediazonium tetrafluoroborate

352-34-1 Downstream products

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    324-74-3

    4-fluoro-biphenyl

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    899-26-3

    tris(4-fluorophenyl)amine

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    330-85-8

    1-fluoro-4-(phenylthio)benzene

  • 398-23-2
    398-23-2

    4,4'-difluorobiphenyl

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