58534-95-5
- Product Name：3-BroMo-2-fluoroaniline
- Molecular Formula：C6H5BrFN
- Purity：99%
- Molecular Weight：190.015
Product Details;
CasNo： 58534-95-5
Molecular Formula： C6H5BrFN
factory and supplier 58534-95-5 3-BroMo-2-fluoroaniline in stock
- Molecular Formula:C6H5BrFN
- Molecular Weight:190.015
- Vapor Pressure:0.077mmHg at 25°C
- Boiling Point:227.514oC at 760 mmHg
- PKA:2.13±0.10(Predicted)
- Flash Point:91.397oC
- PSA：26.02000
- Density:1.695g/cm3
- LogP:2.75160
3-Bromo-2-fluoroaniline(Cas 58534-95-5) Usage
InChI:InChI=1/C6H5BrFN/c7-4-2-1-3-5(9)6(4)8/h1-3H,9H2
58534-95-5 Relevant articles
Preparation and application of indolizine compound
-
Paragraph 0025; 0075-0078, (2021/08/14)
The invention provides an indolizine com...
Discovery of selective fragment-sized immunoproteasome inhibitors
Kollár, Levente,Gobec, Martina,Szilágyi, Bence,Proj, Matic,Knez, Damijan,ábrányi-Balogh, Péter,Petri, László,Imre, Tímea,Bajusz, Dávid,Ferenczy, Gy?rgy G.,Gobec, Stanislav,Keser?, Gy?rgy M.,Sosi?, Izidor
, (2021/04/23)
Proteasomes contribute to maintaining pr...
Indolizine compound as well as preparation method and application thereof
-
Paragraph 0103; 0104; 0105, (2020/07/13)
The invention provides an indolizine com...
TYK2 INHIBITORS AND USES THEREOF
-
Paragraph 00467, (2020/06/19)
The present invention provides compounds...
58534-95-5 Process route
-
-
848440-23-3
(3-bromo-2-fluorophenyl)carbamic acid tert-butyl ester
-
-
58534-95-5
3-bromo-2-fluorobenzenamine
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
1,4-dioxane; water;
at 20 ℃;
for 18h;
|
94% |
|
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 2h;
|
6.5 g |
|
With
trifluoroacetic acid;
In
dichloromethane;
at 22 ℃;
for 2h;
|
6.5 g |
-
3-bromo-2-fluorobenzoic acid
-
161957-56-8
3-bromo-2-fluorobenzoic acid
-
-
58534-95-5
3-bromo-2-fluorobenzenamine
| Conditions | Yield |
|---|---|
|
With
diphenyl phosphoryl azide; triethylamine;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 2h;
|
50% |
|
Multi-step reaction with 2 steps
1: triethylamine; diphenyl phosphoryl azide / toluene / 2 h / 100 °C
2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C
With
diphenyl phosphoryl azide; triethylamine; trifluoroacetic acid;
In
dichloromethane; toluene;
|
|
|
Multi-step reaction with 2 steps
1.1: triethylamine; diphenyl phosphoryl azide / toluene / 2 h / 120 °C
1.2: 2 h / Reflux
2.1: hydrogenchloride / 1,4-dioxane; water / 18 h / 20 °C
With
hydrogenchloride; diphenyl phosphoryl azide; triethylamine;
In
1,4-dioxane; water; toluene;
|
|
|
Multi-step reaction with 2 steps
1.1: triethylamine; diphenyl phosphoryl azide / toluene / 100 °C
1.2: 2 h
2.1: trifluoroacetic acid / dichloromethane / 2 h / 22 °C
With
diphenyl phosphoryl azide; triethylamine; trifluoroacetic acid;
In
dichloromethane; toluene;
|
58534-95-5 Upstream products
-
58534-94-4
2-fluoro-3-bromonitrobenzene
-
161957-56-8
3-bromo-2-fluorobenzoic acid
-
848440-23-3
(3-bromo-2-fluorophenyl)carbamic acid tert-butyl ester
58534-95-5 Downstream products
-
1184298-53-0
N-(3-bromo-2-fluoro-phenyl)-4-chloro-butyramide
-
1192039-95-4
tert-butyl (2E)-3-(3-amino-2-fluorophenyl)prop-2-enoate
-
1192039-96-5
tert-butyl 3-(3-amino-2-fluorophenyl)propanoate
-
1269233-04-6
N-(3-bromo-2-fluorophenyl)propane-1-sulfonamide
Relevant Products
-
5-Bromo-2-fluoroanilineCAS：2924-09-6
-
2-Fluoro-3-nitrotolueneCAS：437-86-5
-
Phenyl propargyl sulfideCAS：5651-88-7
