74316-55-5
- Product Name：5-Bromo-8-methylquinoline
- Molecular Formula：C10H8BrN
- Purity：99%
- Molecular Weight：222.084
Product Details;
CasNo： 74316-55-5
Molecular Formula： C10H8BrN
factory and supplier 74316-55-5 5-Bromo-8-methylquinoline in stock
- Molecular Formula:C10H8BrN
- Molecular Weight:222.084
- Melting Point:37-38 °C
- Boiling Point:315.7±22.0 °C(Predicted)
- PKA:3.95±0.29(Predicted)
- PSA：12.89000
- Density:1.488±0.06 g/cm3(Predicted)
- LogP:3.30570
74316-55-5 Relevant articles
Three-Component Couplings among Heteroarenes, Difluorocyclopropenes, and Water via C-H Activation
Liu, Xuexin,Chen, Jian,Yang, Chunyan,Wu, Zhouping,Li, Zhiyang,Shi, Yuesen,Huang, Tianle,Yang, Zhongzhen,Wu, Yong
supporting information, p. 6831 - 6835 (2021/09/08)
Three-component couplings have been real...
RhIII-Catalyzed Direct Heteroarylation of C(sp3)-H and C(sp2)-H Bonds in Heterocycles with N-Heteroaromatic Boronates
Wang, Huai-Wei,Wu, Jia-Xue,Qiao, Yu-Han,Li, Yong-Fei,Li, Da-Cheng,Dou, Jian-Min,Yao, Qing-Xia,Lu, Yi
supporting information, p. 7177 - 7182 (2021/09/18)
Herein, we disclose a RhIII-catalyzed he...
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
-
Paragraph 00140-00141, (2021/08/06)
Compounds according to formula I are use...
Rh(iii)-Catalyzed straightforward arylation of 8-methyl/formylquinolines using diazo compounds
Ghosh, Bidhan,Samanta, Rajarshi
supporting information, p. 6886 - 6889 (2019/06/18)
A straightforward Rh(iii)-catalyzed gene...
74316-55-5 Process route
-
-
611-32-5
8-methylquinoline
-
-
74316-55-5
5-bromo-8-methyl-quinoline
| Conditions | Yield |
|---|---|
|
With
bromine; silver sulfate;
In
sulfuric acid;
for 0.5h;
|
86% |
|
With
sulfuric acid; bromine; silver sulfate;
at 20 ℃;
for 0.5h;
|
86% |
|
With
sulfuric acid; bromine; silver sulfate;
at 0 - 25 ℃;
for 4h;
|
84% |
|
With
sulfuric acid; bromine; silver sulfate;
at 20 ℃;
for 5h;
|
71% |
|
With
sulfuric acid; bromine; silver sulfate;
at 20 ℃;
for 5h;
|
71% |
|
With
sulfuric acid; bromine; silver sulfate;
at 20 ℃;
for 0.5h;
|
70% |
|
With
N-Bromosuccinimide;
In
sulfuric acid;
at 20 ℃;
for 3h;
|
58% |
|
With
sulfuric acid; bromine; silver sulfate;
In
water;
at 0 - 20 ℃;
for 4h;
|
|
|
With
N-Bromosuccinimide; sulfuric acid;
at 5 ℃;
for 18h;
|
|
|
8-methylquinoline;
With
N-Bromosuccinimide; sulfuric acid;
at 5 ℃;
for 18h;
With
sodium hydroxide;
In
water;
|
-
-
39478-78-9
5-bromo-2-methylaniline
-
-
56-81-5,25618-55-7,64333-26-2,8013-25-0
glycerol
-
-
74316-55-5
5-bromo-8-methyl-quinoline
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; nitrobenzene;
|
|
|
5-bromo-2-methylaniline; glycerol;
With
sulfuric acid; nitrobenzene;
In
water;
at 150 ℃;
for 3h;
With
sodium hydroxide;
In
water;
at 0 ℃;
|
|
|
With
sulfuric acid; sodium iodide;
In
water;
at 140 - 145 ℃;
for 4h;
Inert atmosphere;
Schlenk technique;
|
|
|
With
sulfuric acid; sodium iodide;
In
water;
at 140 - 145 ℃;
for 4h;
Schlenk technique;
|
|
|
With
sulfuric acid; sodium iodide;
In
water;
at 140 - 145 ℃;
for 2.5h;
Inert atmosphere;
Schlenk technique;
|
|
|
With
sulfuric acid; sodium iodide;
at 140 ℃;
for 6h;
|
|
|
With
sulfuric acid; sodium iodide;
In
water;
at 140 - 145 ℃;
for 3.5h;
|
|
|
With
sulfuric acid;
In
nitrobenzene;
at 150 ℃;
for 3h;
|
|
|
With
sulfuric acid; sodium iodide;
at 140 - 145 ℃;
for 3.5h;
|
|
|
With
sulfuric acid; sodium iodide;
In
water;
at 140 - 145 ℃;
for 6h;
|
74316-55-5 Upstream products
-
39478-78-9
5-bromo-2-methylaniline
-
56-81-5
glycerol
-
611-32-5
8-methylquinoline
-
7726-95-6
bromine
74316-55-5 Downstream products
-
74316-57-7
8-methylquinoline-5-carbonitrile
-
74316-52-2
8-methyl-5-quinolinecarboxylic acid
-
1373436-70-4
8-[bis(benzenesulfonyl)aminomethyl]-5-bromoquinoline
-
1575701-49-3
N-[(5-bromoquinolin-8-yl)methyl]-4-methylbenzenesulfonamide
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-
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-
Adipic AnhydrideCAS：2035-75-8
-
5-Norbornene-2,3-dicarboxylic acidCAS：3813-52-3
