630125-49-4
- Product Name：3-Bromo-5-nitrobenzotrifluoride
- Molecular Formula：C7H3BrF3NO2
- Purity：99%
- Molecular Weight：270.006
Product Details;
CasNo： 630125-49-4
Molecular Formula： C7H3BrF3NO2
factory and supplier 630125-49-4 3-Bromo-5-nitrobenzotrifluoride in stock
- Molecular Formula:C7H3BrF3NO2
- Molecular Weight:270.006
- Refractive Index:1.515
- Boiling Point:223.7 °C at 760 mmHg
- Flash Point:89.1 °C
- PSA：45.82000
- Density:1.788 g/cm3
- LogP:3.89930
630125-49-4 Relevant articles
Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group
Fu, Zhengjiang,Jiang, Yongqing,Wang, Shuiliang,Song, Yuanyuan,Guo, Shengmei,Cai, Hu
supporting information, p. 3003 - 3007 (2019/05/10)
A highly regioselective Pd-catalyzed car...
meta-Nitration of Arenes Bearing ortho/para Directing Group(s) Using C?H Borylation
Li, Xuejing,Deng, Xingwang,Coyne, Anthony G.,Srinivasan, Rajavel
supporting information, p. 8018 - 8023 (2019/05/29)
Herein, we report the meta-nitration of ...
Method for preparing nilotinib intermediate
-
Paragraph 0028, (2016/11/14)
Disclosed in the present invention is a ...
An efficient d-glucosamine-based copper catalyst for C-X couplings and its application in the synthesis of nilotinib intermediate
Wen, Ming,Shen, Chao,Wang, Linfang,Zhang, Pengfei,Jin, Jianzhong
, p. 1522 - 1528 (2015/02/18)
d-Glucosamine has been studied for C-N a...
630125-49-4 Process route
-
-
98-46-4
3-trifluoromethylnitrobenzene
-
-
630125-49-4
1-bromo-3-nitro-5-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
|
3-trifluoromethylnitrobenzene;
With
sulfuric acid;
In
dichloromethane; water;
at 35 ℃;
for 0.166667h;
With
1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione;
In
dichloromethane; water;
at 35 ℃;
for 24h;
With
sodium hydroxide;
In
dichloromethane; water;
at 0 - 35 ℃;
for 0.333333h;
|
89.6% |
|
With
sulfuric acid; bromine; nitric acid;
at 70 ℃;
for 4h;
|
|
|
With
sulfuric acid; bromine;
at 60 - 70 ℃;
for 14h;
Cooling with ice;
|
24.7 g |
-
-
320-94-5
2-nitro-4-trifluoromethylbenzoic acid
-
-
630125-49-4
1-bromo-3-nitro-5-(trifluoromethyl)benzene
| Conditions | Yield |
|---|---|
|
With
copper(I) oxide; potassium phosphate; tetrakis(triphenylphosphine) palladium(0); bismuth (III) nitrate pentahydrate; oxygen; sodium bromide;
In
dimethyl sulfoxide;
at 170 ℃;
for 10h;
regioselective reaction;
Schlenk technique;
Green chemistry;
|
38% |
630125-49-4 Upstream products
-
98-46-4
3-trifluoromethylnitrobenzene
-
98-08-8
α,α,α-trifluorotoluene
-
320-94-5
2-nitro-4-trifluoromethylbenzoic acid
-
401-78-5
3-bromo-1-trifluoromethylbenzene
630125-49-4 Downstream products
-
916975-92-3
4-methyl-1-(3-nitro-5-(trifluoromethyl)-phenyl)-1H-imidazole
-
1365803-06-0
tert-butyl 4-[3-nitro-5-(trifluoromethyl)phenyl]- 1,2,3,6-tetrahydropyridine-1-carboxylate
-
861881-13-2
3-(1-methylpiperidin-4-yl)-5-(trifluoromethyl)aniline
-
1365803-07-1
4-(3-nitro-5-(trifluoromethyl)phenyl)-1,2,3,6-tetrahydropyridine
Relevant Products
-
5-Bromo-2-(trifluoromethoxy)anilineCAS：886762-08-9
-
Poly(3-hexylthiophene-2,5-diyl)CAS：104934-50-1
-
5-Oxo-5-(2-thienyl)valeric acidCAS：22971-62-6
