247940-06-3
- Product Name：2-(Dicyclohexylphosphino)biphenyl
- Molecular Formula：C24H31P
- Purity：99%
- Molecular Weight：350.484
Product Details;
CasNo： 247940-06-3
Molecular Formula： C24H31P
Appearance： white to light yellow crystal powder
factory and supplier 247940-06-3 2-(Dicyclohexylphosphino)biphenyl in stock
- Molecular Formula:C24H31P
- Molecular Weight:350.484
- Appearance/Colour:white to light yellow crystal powder
- Vapor Pressure:1.27E-09mmHg at 25°C
- Melting Point:102-106 °C(lit.)
- Boiling Point:499.5 °C at 760 mmHg
- Flash Point:271.7 °C
- PSA：13.59000
- LogP:7.12620
2-(Dicyclohexylphosphino)biphenyl(Cas 247940-06-3) Usage
|
Reaction |
Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates. Ligand employed in Suzuki coupling reactions involving aryl chlorides, bromides and triflates. Useful ligand for the Pd-catalyzed oxidation of alcohols in the presence of chlorobenzenes. Useful ligand for the Pd-catalyzed amination with ammonia equivalents. Ligand for the gold(I)-catalyzed intramolecular [4+2] cycloadditions involving 1,3-enynes and arylalkynes with alkenes. Ligand used in the palladium-catalyzed borylation of aryl bromdies. Ligand used in the palladium-catalyzed siliylation of aryl chlorides. |
|
General Description |
CyJohnPhos [(2-Biphenyl)dicyclohexylphosphine] is an air-stable, bulky and electron-rich monodentate biarylphosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions. |
InChI:InChI=1/C24H31P/c1-4-12-20(13-5-1)23-18-10-11-19-24(23)25(21-14-6-2-7-15-21)22-16-8-3-9-17-22/h1,4-5,10-13,18-19,21-22H,2-3,6-9,14-17H2
247940-06-3 Relevant articles
Palladium-Catalyzed C-P(III) Bond Formation by Coupling ArBr/ArOTf with Acylphosphines
Chen, Xingyu,Wu, Hongyu,Yu, Rongrong,Zhu, Hong,Wang, Zhiqian
, p. 8987 - 8996 (2021/06/30)
Palladium-catalyzed C-P bond formation r...
A Mild One-Pot Reduction of Phosphine(V) Oxides Affording Phosphines(III) and Their Metal Catalysts
Kapu?niak, ?ukasz,Plessow, Philipp N.,Trzybiński, Damian,Wo?niak, Krzysztof,Hofmann, Peter,Jolly, Phillip Iain
supporting information, p. 693 - 701 (2021/04/06)
The metal-free reduction of a range of p...
Rhodium-Catalyzed PIII-Directed ortho-C?H Borylation of Arylphosphines
Wen, Jian,Wang, Dingyi,Qian, Jiasheng,Wang, Di,Zhu, Chendan,Zhao, Yue,Shi, Zhuangzhi
supporting information, p. 2078 - 2082 (2019/02/01)
Transition-metal-mediated metalation of ...
Preparation of Aryl(dicyclohexyl)phosphines by C-P Bond-Forming Cross-Coupling in Water Catalyzed by an Amphiphilic-Resin-Supported Palladium Complex
Hirai, Yoshinori,Uozumi, Yasuhiro
supporting information, p. 2966 - 2970 (2017/10/26)
Aryl(dicyclohexyl)phosphines were prepar...
247940-06-3 Process route
-
-
2052-07-5
2-Bromobiphenyl
-
-
829-84-5
dicyclohexylphosphane
-
-
247940-06-3
CyJohnPhos
| Conditions | Yield |
|---|---|
|
With
bis(η3-allyl-μ-chloropalladium(II)); potassium hydroxide;
In
water;
at 100 ℃;
Inert atmosphere;
|
81% |
-
-
17763-65-4
biphenyl-2-yl trifluoromethanesulfonate
-
-
829-84-5
dicyclohexylphosphane
-
-
247940-06-3
CyJohnPhos
| Conditions | Yield |
|---|---|
|
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
1,2-bis(diphenylphosphino)ethane nickel(II) chloride;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 18.67h;
Product distribution / selectivity;
|
77% |
|
With
1,4-diaza-bicyclo[2.2.2]octane;
1,2-bis(diphenylphosphino)ethane nickel(II) chloride;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 18.67h;
Product distribution / selectivity;
|
8 %Chromat. |
|
With
1,8-diazabicyclo[5.4.0]undec-7-ene;
nickel dichloride;
In
water; N,N-dimethyl-formamide;
at 100 ℃;
for 18.67h;
Product distribution / selectivity;
|
90 %Chromat. |
247940-06-3 Upstream products
-
2052-07-5
2-Bromobiphenyl
-
16523-54-9
chlorodicyclohexylphosphane
-
17763-65-4
biphenyl-2-yl trifluoromethanesulfonate
-
829-84-5
dicyclohexylphosphane
247940-06-3 Downstream products
-
383870-96-0
4-(4-methoxy-3-nitrophenyl)morpholine
-
328919-12-6
2-methyl-2-(4-{2-[5-methyl-2-(2'-trifluoromethyl-biphenyl-4-yl)-oxazol-4-yl]-ethoxy}-phenoxy)propionic acid ethyl ester
-
328919-13-7
2-(4-{2-[2-(2'-fluoro-biphenyl-4-yl)-5-methyloxazol-4-yl]-ethoxy}-phenoxy)-2-methylpropionic acid ethyl ester
-
328919-10-4
2-(4-{2-[2-(2'-methoxy-biphenyl-4-yl)-5-methyloxazol-4-yl]-ethoxy}-phenoxy)-2-methylpropionic acid ethyl ester
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