507476-70-2
- Product Name：5-broMoquinoline-8-carbonitrile
- Molecular Formula：C10H5BrN2
- Purity：99%
- Molecular Weight：233.067
Product Details;
CasNo： 507476-70-2
Molecular Formula： C10H5BrN2
factory and supplier 507476-70-2 5-broMoquinoline-8-carbonitrile in stock
- Molecular Formula:C10H5BrN2
- Molecular Weight:233.067
- Boiling Point:367.6±22.0 °C(Predicted)
- PKA:0.68±0.29(Predicted)
- PSA：36.68000
- Density:1.66±0.1 g/cm3(Predicted)
- LogP:2.86898
507476-70-2 Relevant articles
NUCLEIC ACID-BINDING PHOTOPROBES AND USES THEREOF
-
Paragraph 0042, (2019/06/17)
The present invention relates to photoac...
COMPOUNDS AND METHODS FOR MODULATING RNA FUNCTION
-
Paragraph 0068; 00629, (2018/02/28)
The present invention provides compounds...
POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS
-
Paragraph 00229; 00231, (2017/07/06)
The present invention relates to compoun...
COMPOUNDS AND METHODS OF TREATING RNA-MEDIATED DISEASES
-
Sheet 97/122, (2017/12/27)
The present invention provides compounds...
507476-70-2 Process route
-
-
5-bromoquinoline-8-carbaldehyde oxime
-
-
507476-70-2
5-bromo-quinoline-8-carbonitrile
| Conditions | Yield |
|---|---|
|
With
copper diacetate; acetic acid;
In
acetonitrile;
for 21h;
Reflux;
|
95.6% |
|
With
copper diacetate; acetic acid;
In
acetonitrile;
at 15 ℃;
for 21h;
Reagent/catalyst;
Reflux;
|
95.6% |
|
With
acetic acid;
In
acetonitrile;
for 24h;
Reflux;
|
26% |
-
-
573758-03-9
5-amino-quinoline-8-carbonitrile
-
-
507476-70-2
5-bromo-quinoline-8-carbonitrile
| Conditions | Yield |
|---|---|
|
5-amino-quinoline-8-carbonitrile;
With
hydrogen bromide; sodium nitrite;
In
water;
at 0 ℃;
for 0.5h;
With
hydrogen bromide; copper(I) bromide;
In
water;
at 20 - 100 ℃;
for 1h;
|
51% |
507476-70-2 Upstream products
-
573758-03-9
5-amino-quinoline-8-carbonitrile
-
885267-41-4
5-bromoquinoline-8-carboaldehyde
-
557-21-1
zinc(II) cyanide
507476-70-2 Downstream products
-
1445782-00-2
5-(((3S,4R)-4-(3-(trifluoromethoxy)phenyl)pyrrolidin-3-yl)amino)quinoline-8-carboxamide
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