28177-69-7

  • Product Name:2-Hydroxy-3-nitroacetophenone
  • Molecular Formula:C8H7 N O4
  • Purity:99%
  • Molecular Weight:181.148
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Product Details;

CasNo: 28177-69-7

Molecular Formula: C8H7 N O4

factory and supplier 28177-69-7 2-Hydroxy-3-nitroacetophenone in stock

  • Molecular Formula:C8H7 N O4
  • Molecular Weight:181.148
  • Vapor Pressure:0.0644mmHg at 25°C 
  • Melting Point:98.5-99.5 °C 
  • Boiling Point:223.5°Cat760mmHg 
  • PKA:7.31±0.24(Predicted) 
  • Flash Point:93.1°C 
  • PSA:83.12000 
  • Density:1.38g/cm3 
  • LogP:2.02620 

2-HYDROXY-3-NITROACETOPHENONE(Cas 28177-69-7) Usage

Preparation

Preparation by reaction of boiling 5% aqueous potassium hydroxide on 8-nitrochromone (78%).

InChI:InChI=1/C8H7NO4/c1-5(10)6-3-2-4-7(8(6)11)9(12)13/h2-4,11H,1H3

28177-69-7 Relevant articles

Green synthesis method of 2-hydroxy-3-nitroacetophenone

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Paragraph 0045-0056, (2019/01/07)

The invention discloses a green synthesi...

Synthesis method of 2-hydroxyl-3-nitroacetophenone

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Paragraph 0018; 0022; 0026; 0027; 0028, (2017/04/27)

The invention provides a synthesis metho...

8-nitro-2-four azolyl-4- carbonyl benzene benzopyran synthetic method

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Paragraph 0033; 0034; 0035, (2017/02/24)

The invention relates to a synthesis met...

Design, synthesis and biological evaluation of novel benzopyran sulfonamide derivatives as 5-HT6 receptor ligands

Nirogi, Ramakrishna V. S.,Badange, Rajeshkumar,Reballi, Veena,Khagga, Mukkanti

, p. 2117 - 2124 (2015/11/28)

On the basis of a known pharmacophore mo...

28177-69-7 Process route

1-(5-tert-butyl-2-hydroxy-3-nitrophenyl)ethanone
100245-06-5

1-(5-tert-butyl-2-hydroxy-3-nitrophenyl)ethanone

phenol
108-95-2,27073-41-2

phenol

para-tert-butylphenol
98-54-4

para-tert-butylphenol

2-hydroxy-3-nitroacetophenone
28177-69-7

2-hydroxy-3-nitroacetophenone

Conditions
Conditions Yield
With aluminium(III) triflate; 1,1,2,2-tetrachloroethylene; at 100 - 105 ℃; for 8h; Reagent/catalyst; Temperature; Concentration;
3-Nitroacetophenone
121-89-1

3-Nitroacetophenone

2-hydroxy-3-nitroacetophenone
28177-69-7

2-hydroxy-3-nitroacetophenone

Conditions
Conditions Yield
With palladium diacetate; acetic acid; at 70 - 75 ℃; for 8h; under 7500.75 Torr; Temperature; Reagent/catalyst; Pressure; Autoclave; Green chemistry;
92.7%

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