389890-42-0

  • Product Name:(Trans)-3-aminocyclobutanol
  • Molecular Formula:C9H17 N O3
  • Purity:99%
  • Molecular Weight:187.239
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Product Details;

CasNo: 389890-42-0

Molecular Formula: C9H17 N O3

factory and supplier 389890-42-0 (Trans)-3-aminocyclobutanol in stock

  • Molecular Formula:C9H17 N O3
  • Molecular Weight:187.239
  • Melting Point:112 °C 
  • Boiling Point:303.7±31.0 °C(Predicted) 
  • PKA:12.19±0.40(Predicted) 
  • Flash Point:49.1oC 
  • PSA:58.56000 
  • Density:1.10±0.1 g/cm3(Predicted) 
  • LogP:1.42530 

389890-42-0 Relevant articles

Novel CDK inhibitory compounds, preparation method thereof, pharmaceutical composition for use in preventing or treating CDK relating diseases containing the same as an active ingredient

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Paragraph 0287-0289; 0291, (2018/10/24)

The present invention relates to a novel...

ISOXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF PULMONARY DISEASES AND DISORDERS

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Paragraph 0107, (2017/03/21)

The present disclosure features disclose...

DERIVATIVES OF 3-HETEROARYLISOXAZOL-5-CARBOXYLIC AMIDE USEFUL FOR THE TREATMENT OF INTER ALIA CYSTIC FIBROSIS

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Paragraph 0127, (2016/07/27)

The present disclosure is based, in part...

COMPOUNDS, COMPOSITIONS AND METHODS FOR INCREASING CFTR ACTIVITY

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Paragraph 0148, (2016/11/07)

The present disclosure features compound...

389890-42-0 Process route

trans-3-[(tert-butoxycarbonyl)amino]cyclobutyl 4-nitrobenzoate
871014-16-3

trans-3-[(tert-butoxycarbonyl)amino]cyclobutyl 4-nitrobenzoate

tert-butyl N-[(1r,3r)-3-hydroxycyclobutyl]carbamate
389890-42-0

tert-butyl N-[(1r,3r)-3-hydroxycyclobutyl]carbamate

Conditions
Conditions Yield
With potassium carbonate; In methanol; at 20 ℃;
98%
With water; potassium carbonate; In methanol; for 1.5h; Reflux;
64%
With potassium carbonate; In methanol; water; for 2h; Reflux;
With water; potassium carbonate; In methanol; for 2h; Reflux;
With potassium carbonate; In methanol; water; for 2h; Reflux;
trans-3-hydroxycyclobutanamine hydrochloride
1036260-45-3

trans-3-hydroxycyclobutanamine hydrochloride

di-<i>tert</i>-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

tert-butyl N-[(1r,3r)-3-hydroxycyclobutyl]carbamate
389890-42-0

tert-butyl N-[(1r,3r)-3-hydroxycyclobutyl]carbamate

Conditions
Conditions Yield
With triethylamine; In ethanol; at 20 ℃;

389890-42-0 Upstream products

  • 1036260-45-3
    1036260-45-3

    trans-3-hydroxycyclobutanamine hydrochloride

  • 24424-99-5
    24424-99-5

    di-tert-butyl dicarbonate

  • 871014-16-3
    871014-16-3

    trans-3-[(tert-butoxycarbonyl)amino]cyclobutyl 4-nitrobenzoate

  • 154748-49-9
    154748-49-9

    3-(tert-butyloxycarbonylamino)cyclobutan-1-one

389890-42-0 Downstream products

  • 1458653-34-3
    1458653-34-3

    tert-butyl cis-3-(4-bromo-3,5-dimethylphenoxy)cyclobutylcarbamate

  • 1033710-17-6
    1033710-17-6

    3-(methylamino)cyclobutanol

  • 1392804-89-5
    1392804-89-5

    tert-butyl ((1r,3r)-3-hydroxycyclobutyl)(methyl)carbamate

  • 1205037-95-1
    1205037-95-1

    (1r,3r)-3-aminocyclobutan-1-ol hydrochloride

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