198649-68-2
- Product Name：2-(Trifluoromethoxy)benzyl bromide
- Molecular Formula：C8H6BrF3O
- Purity：99%
- Molecular Weight：255.034
Product Details;
CasNo： 198649-68-2
Molecular Formula： C8H6BrF3O
factory and supplier 198649-68-2 2-(Trifluoromethoxy)benzyl bromide in stock
- Molecular Formula:C8H6BrF3O
- Molecular Weight:255.034
- Vapor Pressure:0.704mmHg at 25°C
- Melting Point:32oC
- Refractive Index:1.4812
- Boiling Point:191.7 °C at 760 mmHg
- Flash Point:86.6 °C
- PSA：9.23000
- Density:1.6 g/cm3
- LogP:3.48010
2-(Trifluoromethoxy)benzyl bromide(Cas 198649-68-2) Usage
|
General Description |
2-(Trifluoromethoxy)benzyl bromide is a chemical compound with the formula C8H6BrF3O. It is a colorless liquid that is commonly used as an intermediate in organic synthesis, particularly in the pharmaceutical and agrochemical industries. 2-(Trifluoromethoxy)benzyl bromide is highly reactive and is often used as a versatile building block in the creation of various chemical compounds. It is known for its strong reactivity and potential as a versatile reagent in chemical reactions. Additionally, 2-(Trifluoromethoxy)benzyl bromide is considered to be toxic and should be handled with care and in accordance with all necessary safety precautions. |
InChI:InChI=1/C8H6BrF3O/c9-5-6-3-1-2-4-7(6)13-8(10,11)12/h1-4H,5H2
198649-68-2 Relevant articles
Para-Selective C-H Borylation of Common Arene Building Blocks Enabled by Ion-Pairing with a Bulky Countercation
Mihai, Madalina T.,Williams, Benjamin D.,Phipps, Robert J.
supporting information, p. 15477 - 15482 (2019/10/11)
The selective functionalization of C-H b...
RORγ MODULATORS
-
Page/Page column 21; 38-39; 66, (2018/04/13)
The invention provides an RORγ receptor ...
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Doebelin, Christelle,Patouret, Rémi,Garcia-Ordonez, Ruben D.,Chang, Mi Ra,Dharmarajan, Venkatasubramanian,Kuruvilla, Dana S.,Novick, Scott J.,Lin, Li,Cameron, Michael D.,Griffin, Patrick R.,Kamenecka, Theodore M.
supporting information, p. 2607 - 2620 (2016/12/09)
The nuclear retinoic acid receptor-relat...
Tocolytic oxytocin receptor antagonists
-
, (2008/06/13)
This invention relates to certain novel ...
198649-68-2 Process route
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175278-07-6
2-trifluoromethoxy-benzyl alcohol
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198649-68-2
2-(trifluoromethoxy)benzyl bromide
| Conditions | Yield |
|---|---|
|
With
phosphorus tribromide;
In
dichloromethane;
at 0 - 20 ℃;
for 16h;
Inert atmosphere;
|
62% |
|
2-trifluoromethoxy-benzyl alcohol;
With
methanesulfonyl chloride; triethylamine;
In
tetrahydrofuran;
With
lithium bromide;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
|
350 mg |
-
CBr4
-
CBr4
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-
175278-07-6
2-trifluoromethoxy-benzyl alcohol
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-
198649-68-2
2-(trifluoromethoxy)benzyl bromide
| Conditions | Yield |
|---|---|
|
With
triphenylphosphine;
|
|
|
With
triphenylphosphine;
|
198649-68-2 Upstream products
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175278-07-6
2-trifluoromethoxy-benzyl alcohol
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94651-33-9
2-(trifluoromethoxy)benzaldehyde
198649-68-2 Downstream products
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960208-73-5
(2S,5R)-2-isopropyl-3,6-dimethoxy-5-(2-trifluoromethoxy-benzyl)-2,5-dihydro-pyrazine
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137218-25-8
2-(2-trifluoromethoxyphenyl)acetonitrile
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1031336-94-3
2-(1,4-dioxaspiro[4.5]decan-8-yl)-5-(5-(2-(trifluoromethoxy)benzyloxy)-1H-pyrazol-3-yl)pyridine
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800407-81-2
(S,R)-1-(4-benzyl-morpholin-2-yl)-1-phenyl-2-(2-trifluorometoxy-phenyl)-ethanol
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