What is the 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine?

2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is , while it's Molecular Formula is C 7 HCl 3 FN 3 . Used in Pharmaceutical Industry: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a key intermediate in the synthesis of new drugs for various therapeutic applications. Its unique structure and reactivity make it a valuable component in the development of novel pharmaceutical compounds. Used in Agrochemical Development: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a building block in the creation of new agrochemicals, such as pesticides and herbicides. Its potential to form stable and effective compounds makes it a promising candidate for use in agricultural applications. Used in Organic Synthesis: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a versatile reagent in organic synthesis, allowing for the formation of a wide range of chemical products. Its unique structure and reactivity contribute to the synthesis of complex molecules and compounds. Used in Material Science: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a component in the development of new materials with specific properties, such as high thermal stability or unique electronic characteristics. Its potential applications in material science could lead to advancements in various industries, including electronics and aerospace.

What is the CAS number for 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine?

The CAS number of 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is 2454396-80-4.

What is 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine (2454396-80-4) used for?

2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is a chemical compound with the molecular formula C8H3Cl3FN4. It is a member of the pyrido[4,3-d]pyrimidine family and is characterized by a pyrimidine ring fused to a pyridine ring. 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is a highly fluorinated aromatic heterocyclic, which can be used in various synthetic processes. It is also recognized for its potential applications in the pharmaceutical industry, particularly in the development of new drugs and agrochemicals. 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine may also have uses in the field of organic synthesis and material science due to its unique structure and reactivity.

What is the 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine?

2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is , while it's Molecular Formula is C 7 HCl 3 FN 3 . Used in Pharmaceutical Industry: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a key intermediate in the synthesis of new drugs for various therapeutic applications. Its unique structure and reactivity make it a valuable component in the development of novel pharmaceutical compounds. Used in Agrochemical Development: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a building block in the creation of new agrochemicals, such as pesticides and herbicides. Its potential to form stable and effective compounds makes it a promising candidate for use in agricultural applications. Used in Organic Synthesis: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a versatile reagent in organic synthesis, allowing for the formation of a wide range of chemical products. Its unique structure and reactivity contribute to the synthesis of complex molecules and compounds. Used in Material Science: 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is used as a component in the development of new materials with specific properties, such as high thermal stability or unique electronic characteristics. Its potential applications in material science could lead to advancements in various industries, including electronics and aerospace.

What is the CAS number for 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine?

The CAS number of 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is 2454396-80-4.

What is 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine (2454396-80-4) used for?

2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is a chemical compound with the molecular formula C8H3Cl3FN4. It is a member of the pyrido[4,3-d]pyrimidine family and is characterized by a pyrimidine ring fused to a pyridine ring. 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine is a highly fluorinated aromatic heterocyclic, which can be used in various synthetic processes. It is also recognized for its potential applications in the pharmaceutical industry, particularly in the development of new drugs and agrochemicals. 2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine may also have uses in the field of organic synthesis and material science due to its unique structure and reactivity.

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2454396-80-4

Product Name：2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine
Molecular Formula：
Purity：99%
Molecular Weight：252.462

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Product Details;

CasNo： 2454396-80-4

factory and supplier 2454396-80-4 2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine in stock

Molecular Formula:C₇HCl₃FN₃
Molecular Weight:252.462

2454396-80-4 Relevant articles

KRAS G12D INHIBITORS

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Paragraph 0200; 0217; 0243, (2022/02/15)

The present invention relates to compoun...

Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12DInhibitor

Wang, Xiaolun,Allen, Shelley,Blake, James F.,Bowcut, Vickie,Briere, David M.,Calinisan, Andrew,Dahlke, Joshua R.,Fell, Jay B.,Fischer, John P.,Gunn, Robin J.,Hallin, Jill,Laguer, Jade,Lawson, J. David,Medwid, James,Newhouse, Brad,Nguyen, Phong,O'Leary, Jacob M.,Olson, Peter,Pajk, Spencer,Rahbaek, Lisa,Rodriguez, Mareli,Smith, Christopher R.,Tang, Tony P.,Thomas, Nicole C.,Vanderpool, Darin,Vigers, Guy P.,Christensen, James G.,Marx, Matthew A.

, p. 3123 - 3133 (2021/12/27)

KRASG12D, the most common oncogenic KRAS...

KRAS G12D INHIBITORS

-

Paragraph 0277; 0279; 0301; 0538, (2021/03/05)

The present invention relates to compoun...

KRAS G12C INHIBITORS

-

Paragraph 0511, (2020/07/25)

The present invention relates to compoun...

2454396-80-4 Process route

: 2454397-75-0
7-Chloro-8-fluoropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione

: 2454396-80-4
2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 110 ℃; for 2h; Temperature; Solvent;	100%
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 110 ℃; for 2h; Temperature; Solvent;	100%
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In toluene; at 0 - 110 ℃; for 5h; Solvent; Temperature;	85.39%
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 0 - 110 ℃; for 3h;
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 100 ℃; for 1h;

: 7-chloro-8-fluoropyrido[4,3-d]pyrimidine-2,4-diol

: 2454396-80-4
2,4,7-trichloro-8-fluoropyrido[4,3-d]pyrimidine

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 0 - 110 ℃; for 6h; Inert atmosphere;
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; In toluene; at 0 - 110 ℃; for 3h; Solvent; Temperature;
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 110 ℃; for 1h;
With N-ethyl-N,N-diisopropylamine; trichlorophosphate; at 110 ℃; for 1h;

2454396-80-4 Upstream products

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tert-butyl (2-chloro-3-fluoropyridin-4-yl)carbamate
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2-chloro-3-fluoro-pyridin-4-ylamine
2454397-75-0
7-Chloro-8-fluoropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione

2454396-80-4 Downstream products

2621928-55-8
4-(4-((1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-(((2R,7aS)-2-fluorohexahydro-1H-pyrrolizin-7a-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol
2621928-55-8
4-(4-(3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-(((2R,7aS)-2-fluorohexahydro-1H-pyrrolizin-7a-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol

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2454396-80-4

Product Details;

factory and supplier 2454396-80-4 2,4,7-Trichloro-8-fluoropyrido[4,3-d]pyrimidine in stock

2454396-80-4 Relevant articles

KRAS G12D INHIBITORS

-

Paragraph 0200; 0217; 0243, (2022/02/15)

Identification of MRTX1133, a Noncovalent, Potent, and Selective KRASG12DInhibitor

, p. 3123 - 3133 (2021/12/27)

KRAS G12D INHIBITORS

-

Paragraph 0277; 0279; 0301; 0538, (2021/03/05)

KRAS G12C INHIBITORS

-

Paragraph 0511, (2020/07/25)

2454396-80-4 Process route

2454396-80-4 Upstream products

2454396-80-4 Downstream products

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